What Is It?
Three amino acids — Glutamate, Cysteine, Glycine. The most abundant antioxidant in your body. Your liver makes 8-10 grams of it every single day. Levels decline 10-15% per decade after age 20.
How Does It Work?
Your liver makes 8 grams of glutathione every single day. From three amino acids you eat in food. Cysteine is the bottleneck. If you're low on cysteine, your factory slows down. Glutathione drops. If you supply more cysteine, the factory runs faster. Glutathione rises. The ingredient matters more than the finished product. Powers cellular energy production, Phase II liver detoxification, recycles vitamins C and E, and supports immune function.
Primary Benefits (research suggests)
- Master antioxidant and detoxification agent
- NAC (N-acetyl cysteine) is the hospital-standard precursor — used since the 1970s for acetaminophen overdose because it replenishes glutathione fast
- Powers Phase II liver detoxification and recycles vitamins C and E
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Open the Calculator →The Honest Part
- Plain oral glutathione doesn't work — 1992 trial showed no blood increase, 2011 RCT showed no rise and no oxidative stress drop.
- GGT in your gut destroys it.
- Most products sold are the ineffective form.
- Liposomal is better but not perfect (~40% raise, vendor-funded studies).
- IV is expensive and effects fade fast.
- Skin-whitening use is unapproved with FDA safety warnings.
- NAC is cheaper, has decades of clinical data, and raises intracellular glutathione via the liver factory.
- For research purposes only.
Research Sources
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