What Is It?
The energy currency your cells spend every second. Declines with age — roughly half by middle age. You can't take NAD+ orally (it breaks down), so you take precursors: NMN (one step from NAD+), NR (two steps), NAM (three steps).
How Does It Work?
NAD+ is the energy currency your cells spend every second. The bucket leaks all day. Aging makes it leak faster. NMN, NR, and NAM are bucket-fillers. They can't be NAD+ themselves. But they get converted into NAD+ inside your cells. Powers ATP production, DNA repair via PARP enzymes, sirtuin activation (longevity genes), and mitochondrial function.
Primary Benefits (research suggests)
- Multiple human trials show NMN 250-900mg/day raises blood NAD+ levels
- Different precursor routes, same destination
- Supports cellular energy, DNA repair, and mitochondrial health
Run the Numbers
Calculate your NAD+ / NMN dosing — capsule strength, daily totals, and protocol planning. Free, no login required.
Open the Calculator →The Honest Part
- 2022 FDA ruled NMN cannot be marketed as a dietary supplement (it's an investigational drug).
- Mouse data is more dramatic than human data.
- Long-term human safety is limited (most trials 12 weeks or less).
- NAD+ IV therapy is unproven.
- For research purposes only.
Research Sources
Verified vendors offering this compound for research purposes. Use code ROCN10 for discounts. We may earn commissions from these links.
Track NAD+ in the App
Peptide Manager Pro tracks 100+ compounds with an interactive knowledge graph, dosing calculator, protocol tracker, and AI research chat. Veteran-owned. $4.99/mo founding rate.
Get the App →