What Is It?
A 4-amino-acid peptide (Ala-Glu-Asp-Gly) synthesized in the 1980s by Vladimir Khavinson. Built from bovine pineal extract. One of the smallest peptides ever studied for longevity.
How Does It Work?
Soviet researchers found bovine pineal extract extended lifespan in animals. Khavinson's team stripped it down, amino acid by amino acid, until they hit four. The smallest piece that still worked. Maximum reduction. Same claim. Activates telomerase (in vitro), extends telomere length, restores pineal melatonin output in aged primates.
Primary Benefits (research suggests)
- 13.3% lifespan extension in aged rats
- Reduced spontaneous tumor incidence
- Telomere lengthening in cell cultures
- Melatonin restoration in aged animals
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- 30 years, 100+ papers, one lab — no Western replication.
- FDA Category 2 (2023) — flagged for safety concerns or insufficient evidence.
- WADA prohibited.
- Theoretical telomerase-cancer risk in occult tumors.
- For research purposes only.
Research Sources
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